Action at the Astrocytes
While serotonin is most well known as an essential brain neurotransmitter, it has been estimated that as much as 95 percent of the body’s serotonin is produced in the digestive tract. Similarly, the hormone melatonin is most well known as being produced by the pineal gland at night based on circadian rhythm factors. However, it’s been observed that the digestive tract contains at least 400 times more melatonin than the pineal gland while having no circadian based secretion cycle. It is believed that melatonin levels in the gut are independent of pineal production since rats with pinealactomy were not effected in terms of their gut melatonin concentrations.
In 2005, the Scandinavian Journal of Clinical and Laboratory Investigation published a new discovery (back then) of large amounts of bufotenine (5-HO-DMT) in the stool samples of humans. The levels of bufotenine in stool samples...
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