by J C

Questions for the Lion Tamer

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A Few Interesting DMT Studies for the Future

There are many perspectives on “The Spirit Molecule” and what it’s natural role in the human body signifies. There are dozens of theories regarding this but as of this moment, without the implementation of scientific scrutiny, it’s difficult to quantify much of them.

I have listed a few studies that I would like to see take place in the future regarding both endogenous DMT measurement and exogenous DMT administration.

1. Measuring DMT Formation in Humans (Endogenous Study)
This study is based on the piece written here at Q4LT that provides an in-depth perspective on systemic changes to human physiology that take place during moments appeared to be linked to endogenous DMT synthesis (dreaming, Wim Hof Method, meditation, hypnosis, out of body experiences, hypnagogia, sleep paralysis, energetic “healers”, fasting, dark room retreats/sensory deprivation). It’s a pretty self explanatory

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Placebo Effect, EEG, & 5-MEO-DMT

“That’s just a placebo effect.”

“It could be placebo.”

“Have you ever heard of the placebo effect?”

The standardized definition of the “Placebo Effect” is as follows… a beneficial effect, produced by a placebo drug or treatment, that cannot be attributed to the properties of the placebo itself, and must therefore be due to the patient’s belief in that treatment.

The scientific establishment has accepted the placebo effect to be a true phenomena observed in thousands of scientific studies across the world. In fact, all drug development is compared versus placebo in order to verify whether the drug provides greater efficacy than the “power of belief”. The mechanisms for which this phenomena transpires has seemingly yet to be fully deciphered. The concept of “belief” having a direct effect on physiology has seemingly perplexed the scientific community. However, since “belief” would

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The DMT-5HT2A Receptor Test… Tricky Business

Serotonin is a neurotransmitter derived from tryptophan and is primarily found in the central nervous system, blood platelets, and the gastrointestinal tract. A receptor is a protein molecule that receives chemical signals (ex: Serotonin) from outside a cell. When these chemical signals bind to a receptor, they cause some form of cellular/tissue response. Each receptor is linked to a specific cellular biochemical pathway. While numerous receptors are found in most cells, each receptor will only bind with molecules of a particular structure (ex: lock and key). Throughout the body, serotonin receptors are abbreviated as 5-HT (5-hydroxytryptamine) receptors. These 5-HT receptors are responsible for modulating the release of numerous neurotransmitters (ex: GABA, dopamine) and hormones (ex: oxycotin, cortisol). In general, serotonin is thought of as contributing to feelings of well-being.

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The Potential Cannabis-DMT Relationship

Tetrahydrocannabinol (THC) is considered to be the primary psychoactive constituent of cannabis. While THC provides a distinct set of subjective as well as physiological effects throughout the body, they are described as being distinctly different than a high-dose DMT experience from exogenous means. Those that have indulged in ingesting DMT or Ayahuasca might claim that there is no comparison between the effects of cannabis and the vaunted “Spirit Molecule”.

Cannabis use has gradually increased in America due to it’s legalization in a few states as well as the implementation of “medical marijuana” laws. With increasingly efficient and optimized cultivation techniques in place, the potency of the plant and secondary products have expanded exponentially. It would seem logical that people begin to report a vast array of different subjective experiences from the plant. Some people have

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The Future of Medicine… VR+EEG+DMT

As a young child, there were a few kids among the masses that exuded the coordination to ride a bicycle without the need for training wheels. “Training wheels” are an additional set of smaller wheels that attach to the rear wheels of a bicycle in order to provide additional stability. This then allows a young child the ability to ride their bikes without fear of falling over. As time progresses and the child develops greater coordination and balance, the training wheels are then removed.

A recent 2016 study published in the journal Scientific Reports observed that 8 chronic spinal cord injury (SCI) paraplegics would experience neurological improvements in addition to regaining voluntary motor control in muscles below the (SCI) level leading to marked improvement in their walking index. This study would take place over 12 months and utilize brain-machine interfaces (BMIs) including

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A Few Random DMT Facts & Speculations

Some people like to make the claim… “DMT is everywhere!”.

While this not might be technically 100% true, the ubiquitousness with which it occurs cannot be denied. Hundreds of plants and every mammal tested thus far have showcased varying levels of “The Spirit Molecule” residing within them. Being that dimethyltryptamine (DMT) is still classified as a Schedule I substance alongside heroin and methamphetamines makes it all the more perplexing.

When the general public hears the word “Ayahuasca”, it generally tends to carry with it connotations of exotic plants found within the Amazonian jungle. This shamanic brew is comprised of plants found within this region that contain DMT and monoamine oxidase inhibitors (MAOIs).

In 2013, the Journal of Agricultural & Food Chemistry published a study regarding the occurrence and distribution of tryptamines in citrus plants. There were 6 different

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Measuring DMT Formation in Humans

(Here is a printer friendly version of this article in PDF format.)

It’s not an all or nothing aspect of life.

Ingesting one “shot” of alcohol has significantly different physical effects on a person compared to ingesting 8 “shots”. The same goes for ingesting a cannabis edible equivalent of 10mg THC versus an 80mg THC dose. This thought process can extend to virtually anything in life… consuming one chicken drumstick vs. eight drumsticks, sleeping one hour vs. eight hours, spending one hour in the sun vs. eight hours, etc. It would seem rather silly to focus solely on the effects of only high-end doses while discarding the varying effects that take place between the low and top end.

In Dr. Rick Strassman’s study outlined in his book “DMT: The Spirit Molecule” there were four different doses (0.05mg/kg, 0.1mg/kg, 0.2mg/kg, and 0.4mg/kg) administered to the majority of volunteers. This

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The Sleep Cycle vs. the “Wim Hof Method”

Let me be clear that this is not a competition between the sleep cycle and the “Wim Hof Method” but rather a basic comparison of both.

Sleep cycles consist of five phases labeled as stages 1, 2, 3, 4, and REM (Rapid Eye Movement) sleep. Stage 1 is considered the beginning of the sleep cycle which is perceived as “light sleep” in which we drift in and out of sleep and can be awakened easily. Stage 2 is characterized as a further increase of slow wave production in the brain and deeper sleep with occasional bursts of rapid waves called sleep spindles. In Stage 3, the slowest brain waves (delta) begin to show their formation interspersed with smaller, faster waves. Stage 4 consists of delta waves exclusively. Both Stages 3 and 4 are characterized as “deep sleep” in which it’s difficult to wake a person. The next stage is REM sleep which we characterize as our predominant “dream” state.

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PDF Version of Q4LT Series

I’ve had numerous requests regarding a printer-friendly version of these blog posts in order for people to be able to read them offline.

I’ve included the 6-part series of DMT & Gamma Waves as well as the Wild Theories Series and interviews with Dr. Rick Strassman and Dr. Steven Barker in the pdf. The entire document is 135 pages and can be found here. In an attempt to alleviate unnecessary excess in printing paper, I have eliminated many pictures associated with each post. Unfortunately this might alter a person’s ability to grasp some of the more outlandish concepts presented in the document.

Feel free to save and share the PDF with whomever you dare to do so.

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The Heart-Brain Connection & DMT

This could have been squeezed into the “Wild Theories” series but I forgot so consider this an “add-on”.

The scientific community looks at the brain as though it is the definitive generator of thought and subsequent actions carried out by the body. It’s not illogical as the concentration of neurons in the brain (100 billion) is by far the most concentrated found within the body. However, while it may sound a bit cheesy to think about the heart in terms of intelligence, there are some intriguing findings as it pertains to this mass of beating muscle located within the chest cavity. While the heart lacks the neuronal density of the brain, it has been cited to house about 40,000 neurons.

In 2002, the Journal of Near-Death Studies published a study in which heart transplant recipients were evaluated in terms of changes to their personalities that parallel that of the donors. The study

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